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Ciprofloxacin is authorised in the world under the following brand names: Bacquinor, Baycip, Bernoflox, Ciflox, Cifloxin, Ciloxan, Ciprinol, Cipro, Cipro I.V., Cipro XL, Cipro XR, Ciprobay, Ciprocinol, Ciprodar, Cipromycin, Ciproquinol, Ciproxan, Ciproxin, Flociprin, Floxin, Ocuflox, Proquin XR, Septicide, Velomonit.

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Ciprofloxacin hydrochloride

Active Ingredient (Generic Name Drug): Ciprofloxacin Hcl

UK Medicine Name US Drug Name
Ciproxin 250 mg Tablets

Ciproxin 500 mg Tablets

Ciproxin 750 mg Tablets

Cipro 250 mg Tablets

Cipro 500 mg Tablets

Cipro 750 mg Tablets

The active substance in this medicine is ciprofloxacin. There are three strengths available containing 250 mg, 500 mg or 750 mg of ciprofloxacin as ciprofloxacin hydrochloride per tablet.

The other ingredients are microcrystalline cellulose, crospovidone, silica colloidal anhydrous, magnesium slearate, hypromellose, macrogol 400 and titanium dioxide (E171).

  • Cipro 250mg Tablets are white or yellowish, 11 mm round, biconvex, film-coated tablets. Scored on both sides and side-wall scored, marked C250, on one side, supplied in blister packs.
  • Cipro 500mg Tablets are white or yellowish, 8.2 x 17 mm oval, biconvex, film-coated tablets. Scored on one side and side-wall scored, C500, on one side, supplied in blister packs.
  • Cipro 750mg Tablets are white or yellowish, 10×19 mm oval, biconvex, film-coaled tablets. Scored on one side and side-wall scored, marked C750, on one side, supplied in blister packs.
  1. What Cipro Tablets are and what are they used for
  2. Before you take Cipro Tablets
  3. How to take Cipro Tablets
  4. Possible side effects

What Cipro Tablets are and what are they used for

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Cipro belongs to a group of medicines called quinolone antibiotics. This medicine is used to treat infections caused by susceptible bacteria, including:

  • Respiratory tract infections;
  • Sexually transmitted diseases (STD’s), including gonorrhoea;
  • Kidney and urinary tract infections;
  • Severe gastroenteritis;
  • Skin and soft tissue infections,
  • Bone or joint infections;
  • Severe systemic infections;
  • Acute lung infections in children and adolescents (5 to 17 years) with cystic fibrosis.

Before you take Cipro Tablets

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Do not take Cipro Tablets and talk to your doctor if:

  • you are sensitive (allergic) to ciprofloxacin, other quinolone antibiotics or any of the other ingredients in these tablets;
  • you are or might be pregnant, or you are breast feeding:
  • you have previously had tendon disorders when you took similar antibiotics; .
  • you have epilepsy, convulsions, or a history of central nervous system disorders
  • you experience severe or persistent diarrhoea during or after taking this medicine;
  • you or a family member have a defect in glucose-6-phosphate dehydrogenase activity (an enzyme);
  • you are diagnosed with tendonitis (inflammation of a tendon);
  • you suffer from myasthenia gravis (a neuromuscular disorder characterised by weakness);
  • you are a child or under 18 years of age.

Take special care with Cipro Tablets:

  • If you are going to have an operation, dental treatment, or surgery involving an anaesthetic, let the doctor or dentist know that you are taking Cipro Tablets as certain premedicants are not recommended for use with ciprofloxacin, the active ingredient in Cipro Tablets.
  • Avoid prolonged exposure to sunlight or artificial UV light (e.g. solariums) during treatment with ciprofloxacin, if this cannot be avoided, use a strong sunscreen or sun block product. If you suffer from any sensitivity to sunlight or artificial UV light, you should see your doctor as soon as possible to review your treatment.

It is important to drink plenty of fluids and avoid dehydration.

Cipro tablets may interfere with some blood or urine tests so let your doctor know you are taking this medicine.

Taking Cipro Tablets with food and drink:

The tablets can be taken at any time, with or without food, however dairy products with a high calcium content (e.g. milk, yoghurt) may delay the absorption of ciprofloxacin. You should therefore avoid eating dairy products for 4 hours before and 2 hours after taking your tablets.

Avoid caffeine (e.g. coffee, tea) while taking ciprofloxacin, as this may produce undesirable effects.

Avoid drinking alcohol while taking ciprofloxacin, especially) if you are driving or operating machinery.

Pregnancy

If you are pregnant or think you may be pregnant, do not take Cipro as it may harm your baby.

Breast-feeding

If you are breast-feeding, do not take Cipro as it may harm your baby.

Driving and using machines

This medicine should not make you drowsy. However, you should not drive or operate machinery if you feel dizzy or that your concentration is impaired while taking this medicine.

Taking other medicines:

Please inform your doctor or pharmacist if you are taking or have recently taken any other medicines, even those not prescribed particularly:

  • Theophylline (for wheeziness or asthma);
  • Pentoxifylline (for vascular diseases);
  • Oral anticoagulants such as warfarin (to prevent blood clots);
  • Non-steroidal antiinflammatory drugs (NSAIDs) such as fenbufen for pain and mflanimation;
  • Ciclosporin (to prevent transplant rejection);
  • Probenecid (used mainly to treat gout);
  • Melodopramide (for digestive disorders, sickness, and certain conditions which occur after surgery);
  • Glibenclamide (an anti-diabetic agent).
  • Mexiletine (for heart arrythmias);
  • Phenytoin (lo prevent epilepsy);
  • Sucralfate (for intestinal ulcers or gastritis),
  • Diazepam (mainly used to reduce anxiety and aid sleep);
  • Ropinirole (to treat Parkinson’s disease);
  • Premedicants e.g. papaveretum, atropine or hyoscine (given before surgery);
  • Didanosine (an antiviral medicine);

Your doctor may recommend that you do not take any magnesium, aluminium, calcium, iron or zinc containing medicines while taking ciprofloxacin, e.g. antacids (for indigestion and heartburn) or multivitamin/mineral tablets. If you do take these medicines they should be taken at least 4 hours before or 2 hours after Cipro. Tell your pharmacist that you are taking ciprofloxacin when buying any other medicines.

How to take Cipro Tablets

When you buy cheap Ciprofloxacin you must know how to use it

Always follow your doctor’s instructions as to how and when to take your medicine, your pharmacist may be able to advise you if you are not sure. Exactly how many tablets, and how often you must take them, will be written on the label. Please read it carefully. The recommended doses are given below. However, doctors sometimes prescribe different doses to these; if this applies to you, discuss it with your doctor, if you have not already done so, Swallow the tablets whole with plenty of water. Unless otherwise specified, the usual treatment period is 7 to 14 days.

Adults

  • Chest and lung infections: 250 – 500 mg twice daily.
  • Cystitis (women only); 100 – 250 mg twice daily for three days.
  • Other infections of the urinary tract (kidneys, bladder etc.): 250 – 500 mg twice daily.
  • Prostatitis (infection of the prostate gland – men only): 500 mg twice daily for up to one month.
  • Gonorrhoea: 250 mg – 500 mg as a single dose.
  • Severe gastro-enteritis (stomach upsets usually with vomiting and diarrhoea): 500 mg twice daily for 3 to 7 days.
  • Skin and soft tissue (skin/muscle) infections: 500 mg twice daily for 5-10 days.
  • Bone and joint infections: 500 mg twice daily for d to 6 weeks or longer.
  • Severe systemic (whole body) infections; 500 mg – 750 mg twice daily.

In some severe infections the standard dose may be increased to 750 mg twice a day if necessary.

Elderly

Elderly patients will receive a dose depending on the severity of the disorder and on their kidney function. This may therefore be lower than the standard doses stated above.

Children and adolescents

Cipro Tablets are generally unsuitable for children and adolescents (5-17 years of age) except in specific cases such as cystic fibrosis. The dose required will be worked out by the doctor depending on the child/a doles cents body weight.

Patients with reduced kidney function

If you have reduced kidney function, the doctor may reduce your dose by half or monitor the levels of drug in your blood and adjust your dose accordingly. This applies particularly if you are on haemodialysis or continuous ambulatory peritoneal dialysis (CAPD), when the maximum dose would be 500 mg once a day. If you have a liver problem in addition to reduced kidney function the dose will need to be reduced accordingly.

Take your medicine at regular intervals. Take your medicine for as long as directed by your doctor, even if you feel better, or the infection may return.

If you take more Cipro Tablets than you should:

If you have taken one extra dose this is unlikely to cause problems. If you or someone else has taken more than one extra dose or an overdose of Cipro Tablets, seek medical advice immediately and take your tablets or the box with you to show the doctor if possible.

If you forget to take Cipro Tablets:

If you have forgotten to take your medicine, take the missed dose as soon as you remember.

However, if it is nearly time for your next dose, take a single dose and skip the next dose. Do not take a double dose to make up for forgotten individual doses. If you are at all concerned, consult your doctor or pharmacist.

Possible side effects

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Like all medicines, Cipro can cause side effects, although not everybody gets them. The most common side effects are feeling sick, diarrhoea, vomiting, indigestion, stomach-ad wind, loss of appetite, dizziness, headaches, tiredness, tremor, restlessness and confusion.

Less common side effects are heart palpitations, pain or swelling of the joints, hiccoughs, nose bleeds and build up of fluid in the lungs causing shortness of breath.

Abnormalities of the blood which may result in dizziness, tiredness and making you more prone to minor infections. You should tell your doctor as soon as possible.

Other very rare effects are distortion or absence of the sense of smell and impaired taste, which normally resolves at the end of treatment with Cipro, difficulties sleeping, increased sweating, numbness, swelling of the hands and feet, fits, fainting, fast heartbeat, hot flushes, anxiety, nightmares, distress, weakness, depression, muscle pains, uncontrollable movement of the limbs, ringing in the ears or impaired hearing, visual disturbances, skin reactions including small red spots, blood blisters, small raised lumps which may scab particularly on the legs, severe skin reactions including Stevens-Johnson Syndrome and sensitivity to light (see also “Take Special Care with this Medicine”).

There have been isolated cases of muscle weakness, crystalluria (pain or discomfort when passing water), blood in the urine, increased blood sugar resulting in feeling thirsty and a need to urinate more often which may need treatment by your doctor. Also reported is inflammation of the tendons (particularly the Achilles tendon), if you experience these symptoms, rest the affected limb, discontinue treatment and seek medical advice immediately.

Some people may be allergic to Cipro Tablets. If this is the case, a reaction usually occurs shortly after you take the tablets. Very rarely these allergic reactions can be life threatening. If you experience any wheeziness, difficulty breathing, fever, swelling of the eyelids, face or lips rash or itching (especially of the whole body) you should stop taking this medicine and seek immediate medical advice.

There have been reported cases of pulmonary embolism symptoms of which include chest pains shortness of breath, palpitations and coughing up blood. Also reported is a condition called “Pseudomembranous colitis”, (which causes attacks of diarrhoea, sometimes containing blood and/or mucus), severe headaches or migraines, liver problems (e.g. yellowing of skin and whites of eyes) and kidney problems (decreased urinary frequency). These are potential serious side effects and you will need to seek urgent medical attention.

In isolated cases, some poop c rimy experience paranoia, hallucinations, unclear speech and disorganised and restless behaviour (involving in some cases a risk of self-injury). If you experience these symptoms, stop taking your tablets and see your doctor immediately.

Long-term and repeated use of Cipro can lead to infections with bacteria or fungi which do not respond to treatment.

If any of the side effects gets serious, or If you notice any side effects not mentioned in this leaflet, please inform your doctor or pharmacist.

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Synonyms of Ciprofloxacin:

Ciprofloxacin, Ciprofloxacin Dihydrochloride, Ciprofloxacin HCl, Ciprofloxacin Hydrochloride, Ciprofloxacin Monohydrochloride, Ciprofloxacina

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Therapeutic classes of Ciprofloxacin:

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