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Clarithromycin is authorised in the world under the following brand names: Biaxin, Biaxin XL, Klacid, Klaricid, Macladin, Naxy, Veclam, Zeclar.

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Clarithromycin 250mg, 500mg Tablets [US: Biaxin]

Clarithromycin belongs to a group of medicine called macrolide antibiotics. Antibiotics stop the growth of bacteria (bugs) which cause infections. Clarithromycin tablets are used to treat following infections: chest infections such as bronchitis and pneumonia, throat and sinus infections, skin and soft tissue infections, helicobacterpylori infections associated with duodenal ulcers.

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Each Klaricid XL tablet contains 500 mg of the active ingredient clarithromycin. Klaricid belongs to a group of medicines called macrolide antibiotics. Antibiotics stop the growth of bacteria (bugs) which cause infections.

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See also Macrolide antibiotics Clarithromycin is a commonly used macrolide antibiotic and is a regular part of regimens for the eradication of Helicobacter pylori, often in combination with a nitromidazole antibiotic as well, in addition to a proton pump inhibitor. Variable rates of adverse events (4-30%) have been reported with clarithromycin.

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In three patients with pulmonary MAC and aspergillosis infections, itraconazole was suggested to increase the plasma concentration of clarithromycin as well as the clarithromycin:14-hydroxyclarithromycin ratio. This effect may have been due to inhibition of CYP3A4 by itraconazole. Cisapride can prolong the QT interval, with a risk of ventricular dysrhythmias. Clarithromycin increases serum concentrations of cisapride.

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Intravenous clarithromycin caused thrombophlebitis in four patients when it was given inappropriately as a rapid bolus injection instead of a short infusion; the manufacturers have received other reports of similar reactions, even with infusions, but the incidence seems to be considerably lower than with erythromycin. In a prospective, non-randomized study, phlebitis occurred in 15 of 19 patients treated with intravenous erythromycin (incidence rate of 0.40 episodes/patient-day) and in 19 of 25 patients treated with intravenous clarithromycin (0.35 episodes/patient-day).

Chlamydia Pneumoniae

Chlamydia pneumoniae an obligate intracellular bacteria, has been established as an important cause of adult respiratory disease including pneumonia, bronchitis, sinusitis and pharyngitis. There is no animal reservoir. Incidence/Prevalence in USA: Estimated incidence of 100 to 200 cases of pneumonia/100,000/ year.

Specific Anti-Infective Agents

Clinicians should be familiar with the general classes of antibiotics, their mechanisms of action, and their major toxicities. The differences between the specific antibiotics in each class can be subtle, often requiring the expertise of an infectious disease specialist to design the optimal anti-infective regimen. The general internist or physician-in-training should not attempt to memorize all the facts outlined here, but rather should read the pages that follow as an overview of anti-infectives. The chemistry, mechanisms of action, major toxicities, spectrum of activity, treatment indications, pharmacokinetics, dosing regimens, and cost are reviewed.

Antimicrobial therapy: general principles

A wide variety of antimicrobial agents is available to treat established infections caused by bacteria, fungi, viruses, or parasites. This section will cover the general principles of antimicrobial therapy and will also include illustrative clinical problems to emphasize proper decision-making in using antimicrobials.

Purchase Amoxicillin (Amoxil) No Prescription 500mg

Amoxicillin is used for the treatment of acute otitis media (AOM) caused by S. pneumoniae, H. influenzae, or M. catarrhalis. Amoxicillin usually is considered the drug of first choice for initial treatment of AOM, unless the infection is suspected of being caused by b-lactamase-producing bacteria resistant to the drug, in which case amoxicillin and clavulanate potassium is recommended.

Dosage forms of Clarithromycin:
Clarithromycin 100% powder Biaxin Bid 250 mg Tablet Mylan-Clarithromycin 500 mg Tablet Pms-Clarithromycin 500 mg Tablet
Ratio-Clarithromycin 500 mg Tablet Sandoz Clarithromycin 500 mg Tablet Biaxin Xl 500 mg Extended-Release Tablet Biaxin Bid 500 mg Tablet
Clarithromycin 250 mg tablet Clarithromycin 500 mg tablet Clarithromycin er 500 mg tablet Clarithromycin 500 mg 24 Hour tablet
Biaxin 500 mg tablet Biaxin 250 mg tablet Biaxin xl 500 mg tablet Biaxin XL 500 mg 24 Hour tablet
Clarithromycin 125 mg/5ml Suspension 50ml Bottle Clarithromycin 125 mg/5ml Suspension 100ml Bottle Clarithromycin 250 mg/5ml Suspension 50ml Bottle Clarithromycin 250 mg/5ml Suspension 100ml Bottle
Biaxin 60 250 mg tablet Bottle Biaxin 25 mg/ml Suspension Biaxin 50 mg/ml Suspension  

Synonyms of Clarithromycin:

CLA, Clarithromycine, Clathromycin

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Therapeutic classes of Clarithromycin:

Anti-Bacterial Agents, Macrolides, Other Macrolides, Protein Synthesis Inhibitors

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