Tags: Ethionamide

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Ethionamide is authorised in the world under the following brand names: Aethionamidum, Aetina, Aetiva, Amidazin, Amidazine, Atina, Bayer 5312, Ethimide, Ethina, Etimid, Etiocidan, Etionid, Etionizin, Etionizina, Etionizine, Fatoliamid, Iridocin, Iridozin, Isothin, Isotiamida, Itiocide, Nicotion, Nisotin, Nizotin, Rigenicid, Sertinon, Teberus, Thianid, Thianide, Thioamide, Thiomid, Thioniden, Tianid, Tio-Mid, Tiomid, Trecator, Trecator-SC, Trekator, Trescatyl, Trescazide, Tubenamide, Tubermin, Tuberoid, Tuberoson.

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Other Mycobacteria

The increasingly relative importance of the atypical mycobacteria, many of which are ubiquitous in the environment, was recognized with the decline in tuberculous disease. Generally, atypical mycobacteria are unusual causes of disease in patients who are immunocompetent but can in immunocompromised hosts such as AIDS and cancer patients.

Tuberculosis

Approximately one-third of the world’s population is infected with M tuberculosis, according to World Health Organization estimates, resulting in 2.9 million annual deaths. In the United States, tuberculosis is on the rise, after several decades of steady decline.

Pulmonary Infections

Acute pneumonia is a potentially life-threatening illness requiring rapid diagnosis and treatment. A delay in antibiotic treatment increases the risk of a fatal outcome. Annually, 2 to 3 million cases of pneumonia are reported in the United States.

Treatment of Tuberculosis

Recommended Drug Regimens for Treatment of Latent Tuberculosis Infection. Drug Regimens for Culture-Positive Pulmonary Tuberculosis Caused by Drug-Susceptible Organisms. Doses of Antituberculosis Drugs for Adults and Children. Tuberculous meningitis and Extrapulmonary disease.

Central Nervous System Infections

Central nervous system infections include a wide variety of clinical conditions and etiologies: meningitis, meningoencephalitis, encephalitis, brain and meningeal abscesses, and shunt infections. The focus of this chapter is meningitis. N. meningitidis meningitis is the leading cuase of bacterial meningitis in children and young adults in the United States.

Infectious disorders

Infectious diseases comprise those illnesses that are caused by microorganisms or their products. Clinical manifestations of infection occur only when sufficient tissue injury has been inflicted directly by microbial products (e.g., endotoxins and exotoxins), or indirectly by host responses (e.g., cytokines and hydrolytic enzymes released by polymorphonuclear leukocytes). Despite the extraordinary recent advances that have occurred in therapeutics for infectious diseases, a number of basic principles should be followed to prescribe antimicrobials and vaccines is an optimal manner.

Antimicrobial therapy: general principles

A wide variety of antimicrobial agents is available to treat established infections caused by bacteria, fungi, viruses, or parasites. This section will cover the general principles of antimicrobial therapy and will also include illustrative clinical problems to emphasize proper decision-making in using antimicrobials.

Management of Tuberculosis

Tuberculosis was a disappearing disease in North America until the early 1980s. However, the spread of human immunodeficiency virus infection has changed that. From 1985 to 1992 there was an increase in the number of cases of tuberculosis reported in the United States, and most of these cases were in New York, New Jersey, Texas, Florida, and California. The other major change in the epidemiology of tuberculosis has been the emergence of multidrug-resistant disease.

Management of Malaria

Malaria is a protozoan (genus Plasmodium) infection transmitted by the bite of an infected female Anopheles mosquito and rarely via a contaminated blood transfusion. It is extremely common, affecting more than 500 million persons and resulting in more than 1 million deaths each year. There are four species of the genus Plasmodium that cause malaria in man.

Dosage forms of Ethionamide:
Trecator-SC 250 mg tablet Trecator 250 mg tablet

Synonyms of Ethionamide:

ET, ETH, Ethinamide, Ethionamid Prothionamid, Ethionamidum [INN-Latin], Ethioniamide, Ethylisothiamide, Ethyonomide, Etionamid, Etionamida [INN-Spanish], Etionamide [DCIT], Etioniamid, ETP

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Therapeutic classes of Ethionamide:

Antitubercular Agents, Fatty Acid Synthesis Inhibitors, Leprostatic Agents

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