Tags: Minocin

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Minocycline is authorised in the world under the following brand names: Alti-Minocycline, Apo-Minocycline, Arestin, Dynacin, Gen-Minocycline, Klinomycin, Minociclina [INN-Spanish], Minocin, Minocyclin, Minocycline HCl, Minocyclinum [INN-Latin], Minocyn, Minomycin, Novo-Minocycline, Solodyn, Vectrin.

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The syndrome of pseudotumor cerebri consists of symptoms and signs of raised intracranial pressure in the absence of neuroimaging or cerebrospinal fluid abnormalities. Most cases are idiopathic, but several drugs have been implicated as causative or contributory. The first description of minocycline-related pseudotumor cerebri was published in 1978. Further data have been published concerning 12 patients who developed pseudotumor cerebri after taking standard doses of minocycline for acne vulgaris.

Specific Anti-Infective Agents

Clinicians should be familiar with the general classes of antibiotics, their mechanisms of action, and their major toxicities. The differences between the specific antibiotics in each class can be subtle, often requiring the expertise of an infectious disease specialist to design the optimal anti-infective regimen. The general internist or physician-in-training should not attempt to memorize all the facts outlined here, but rather should read the pages that follow as an overview of anti-infectives. The chemistry, mechanisms of action, major toxicities, spectrum of activity, treatment indications, pharmacokinetics, dosing regimens, and cost are reviewed.

Antimicrobial therapy: general principles

A wide variety of antimicrobial agents is available to treat established infections caused by bacteria, fungi, viruses, or parasites. This section will cover the general principles of antimicrobial therapy and will also include illustrative clinical problems to emphasize proper decision-making in using antimicrobials.

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Minocycline hydrochloride usually is administered orally. When oral therapy is not feasible, the drug may be given by IV infusion; however, oral therapy should replace IV therapy as soon as possible. If minocycline is given IV, the risk of thrombophlebitis should be considered.

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The widespread use of tetracyclines has resulted in a steady increase in the prevalence of resistance to these agents. Therefore, empiric use of tetracycline is usually restricted to regions where resistance levels remain low or to cases where other appropriate antibiotics are contraindicated. Although some tetracyclines have very low activity against S. pneumoniae, doxycycline maintains good antipneumococcal activity and is the tetracycline most commonly used for treatment of bacterial community-acquired pneumonia.

Tetracyclines

Tetracyclines are the prototypical broad-spectrum antibiotic and are occasionally used as first-line agents in some markets (e.g., Germany) for the treatment of mild acute exacerbations of chronic bronchitis, particularly when cost, penicillin hypersensitivity, and β-lactam resistance are of concern. The widespread use of tetracyclines has resulted in a steady increase in the prevalence of resistance to these agents. Therefore, empiric use of tetracyclines is usually restricted to regions where resistance levels remain low or when other appropriate antibiotics are contraindicated.

Acute Exacerbations of Chronic Bronchitis: Current therapies

TABLE: Pharmacological Management of Underlying Disease During an Acute Exacerbation of Chronic Bronchitis summarizes the general pharmacological agents and classes used to manage acute exacerbations of chronic bronchitis. The primary therapies used in acute exacerbations of chronic bronchitis treat the causative infection (antibiotics), relieve symptoms (bronchodilators), and treat the underlying inflammation (corticosteroids). TABLE: Current Therapies Used for Acute Exacerbations of Chronic Bronchitis summarizes the leading antibiotic therapies used to treat the infection.

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The name of your medicine is Sebact MR [Minocin] 100mg Capsules. Each capsule contains 100mg of the active substance minocycline as minocycline hydrochloride. Sebact MR [Minocin] also contains the following other ingredients: microcrystalline cellulose, croscarmellose sodium, povidone, iron oxide red (E172), iron oxide yellow (E172), silica colloidal anhydrous, magnesium stearate, hypromellose phthalate, triethyl citrate, carnauba wax, gelatin, Opadry OY-S-24932 pink which contains hypromellose 2910, macrogol 6000. titanium dioxide (E171), talc, iron oxide red (E172). Sebact MR [Minocin] 100 mg capsules are brown and cream coloured hard capsules that are available in packs of 56 in foil blister strips.

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Minocycline has a spectrum of activity and mode of action similar to that of tetracycline but it is more active against many species including Staphylococcus aureus, streptococci, Neisseria meningitidis, various enterobacteria, Acinetobacter, Bacteroides, Haemophilus, Nocardia, and some mycobacteria, including M. leprae.

Dosage forms of Minocycline:
Apo-Minocycline 100 mg Capsule Minocycline 100 mg Capsule Mylan-Minocycline 100 mg Capsule Novo-Minocycline 100 mg Capsule
Pms-Minocycline 100 mg Capsule Ratio-Minocycline 100 mg Capsule Sandoz Minocycline 100 mg Capsule Minocin 100 mg Capsule
Minocycline HCl 50 mg capsule Minocycline 75 mg capsule Minocycline HCl 75 mg capsule Minocycline hcl 50 mg tablet
Minocycline HCl 100 mg capsule Dynacin 50 mg capsule Minocycline hcl 75 mg tablet Minocin 50 mg capsule
Minocin 50 mg pelletized cap Minocycline hcl 100 mg tablet Dynacin 75 mg capsule Dynacin 50 mg tablet
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Minocycline HCl 135 mg 24 Hour tablet Minocycline HCl 45 mg 24 Hour tablet Minocycline hcl powder Solodyn er 115 mg tablet
Solodyn er 135 mg tablet Solodyn er 45 mg tablet Solodyn er 65 mg tablet Solodyn er 90 mg tablet
Solodyn 135 mg 24 Hour tablet Solodyn 45 mg 24 Hour tablet Solodyn 65 mg 24 Hour tablet Solodyn 90 mg 24 Hour tablet
Arestin 1 mg microsphere Minocin 100 mg vial Minocin kit 50 mg combo Minocin kit 100 mg combo
Minocin PAC 100 mg Kit Box Apo-Minocycline 50 mg Capsule Minocycline 50 mg Capsule Mylan-Minocycline 50 mg Capsule
Novo-Minocycline 50 mg Capsule Pms-Minocycline 50 mg Capsule Ratio-Minocycline 50 mg Capsule Sandoz Minocycline 50 mg Capsule
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Synonyms of Minocycline:

Minocycline

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Therapeutic classes of Minocycline:

Anti-Bacterial Agents, Tetracyclines

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